Endocrine Abstracts

Background: Orlistat is a lipase inhibitor used in the treatment of obesity. Recent published work has shown that orlistat may have a role in affecting the release of appetite regulating gastrointestinal derived peptides. However, the precise effect of orlistat on these hormones remains uncertain. This study aimed to evaluate the short-term effects of orlistat with a high fat meal on levels of plasma Peptide YY (PYY) and on appetite.Methods: Ethical perm...